| Identification | Back Directory | [Name]
MLN-4760 | [CAS]
305335-31-3 | [Synonyms]
MLN-4760
((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine
L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]- | [Molecular Formula]
C19H23Cl2N3O4 | [MDL Number]
MFCD30532572 | [MOL File]
305335-31-3.mol | [Molecular Weight]
428.31 |
| Hazard Information | Back Directory | [Definition]
ChEBI: MLN-4760 is a L-histidine derivative that is L-histidine in which a hydrogen of the primary amino group is substituted by a (1S)-1-carboxy-3-methylbutyl group and the ring NH group is substituted by a 3,5-dichlorobenzyl group. It is a potent and selective human angiotensin-converting enzyme 2 (ACE2) inhibitor (IC50 = 0.44 nM) which was in clinical development for the treatment of ulcerative colitis. It has a role as an anti-inflammatory agent and an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. It is a L-histidine derivative, a dichlorobenzene and a L-leucine derivative. | [storage]
Store at -20°C |
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Binhai gill polypeptide co. LTD
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021-61263389 13524856427 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList326362/0.htm |
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