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ChemicalBook--->CAS DataBase List--->300561-58-4

300561-58-4

300561-58-4 Structure

300561-58-4 Structure
IdentificationBack Directory
[Name]

(±)-SKF-77434 hydrobromide, (±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
[CAS]

300561-58-4
[Synonyms]

SKF-77434 HBr
SKF 77434;SKF-77434;SKF77434
(±)-SKF-77434 hydrobromide, (±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
[Molecular Formula]

C19H22BrNO2
[MDL Number]

MFCD00243077
[MOL File]

300561-58-4.mol
[Molecular Weight]

376.29
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

ethanol: soluble3.2mg/mL
[form ]

solid
[color ]

white to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

N-Allyl-(+/-)-SKF-38393 hydrobromide is a selective dopamine D1-like receptor partial agonist.
[Definition]

ChEBI: N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide is a hydrobromide salt prepared from N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol and one equivalent of hydrogen bromide. Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo. It has a role as a dopamine agonist and a prodrug. It contains a N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepinium-7,8-diol(1+).
[storage]

Store at -20°C
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