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ChemicalBook--->CAS DataBase List--->2999629-35-3

2999629-35-3

2999629-35-3 Structure

2999629-35-3 Structure
IdentificationBack Directory
[Name]

SLF1081851 hydrochloride
[CAS]

2999629-35-3
[Synonyms]

SLF1081851 hydrochloride
[Molecular Formula]

C21H33N3O.ClH
[MOL File]

2999629-35-3.mol
[Molecular Weight]

379.97
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

powder
[color ]

white to beige
Hazard InformationBack Directory
[Biological Activity]

Potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter.
Spns2 inhibitor 16d (SLF1081851) is a potent and selective inhibitor of Spns2 (spinster homolog 2) sphingosine-1-phosphate (SP1) transporter. Spns2 inhibitor 16d (SLF1081851) decreases circulating plasma S1P and lymphocytes in mice and rats. Apparentlyit locks Spns2 in the inward-facing state.
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