| Identification | Back Directory | [Name]
Isoprenaline sulphate | [CAS]
299-95-6 | [Synonyms]
aleudrin
Novodrin
Novodrine
medihaler-iso
ISOPRENALINE SULFATE
isoprenalinesulphate
ISOPROTERENOL SULFATE
ISO PROTERENOL SULPHATE
dl-Isoprenaline sulfate
dl-Isoproterenol sulfate
isoprenalinesulfate(2:1)
isoproterenolsulfate(2:1)
Isoprenaline Sulfate
Isoprenaline sulfuric acid
Isoproterenol sulfuric acid
ISOPRENALINE HEMISULFATE SALT
(-)-ISOPROTERENOL HEMISULFATE
n-isopropylnorepinephrinesulfate
N-ISOPROPYLNORADRENALINE SULFATE
4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol
dl-a-3,4-Dihydroxyphenyl-b-iso-propylaminoethanol sulfate
1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol sulfate (2:1)
1-(3,4-DIHYDROXYPHENYL)-2-ISOPROPYLAMINOETHANOL HEMISULFATE SALT
3,4-dihydroxy-alpha-((isopropylamino)methyl)benzylalcoholsulfate(2:1)
2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-sulfate(2:1)
3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohosulfate(2:1)(s
4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol sulfate (2:1) | [EINECS(EC#)]
206-085-2 | [Molecular Formula]
2C11H17NO3.H2O4S | [MDL Number]
MFCD00013139 | [MOL File]
299-95-6.mol | [Molecular Weight]
520.6 |
| Hazard Information | Back Directory | [Originator]
Isonorin,Smith, Miller and Patch,US,1949 | [Uses]
Bronchodilator. | [Manufacturing Process]
As described in US Patent 2,308,232, 100 g 3,4-dihydroxy-ω-
chloroacetophenone, 200 cc ethyl alcohol and 200 cc of about 50% aqueous
isopropylamine solution are boiled during 3 hours on the water bath with the
use of a reflux condenser, whereupon neutralizing with diluted sulfuric acid is
carried out and the sulfate, obtained upon cooling, from alcohol of 50% is
recrystallized; its MP is 245°C.
21 g 3,4-dihydroxy-ω-isopropylaminoacetophenone sulfate are hydrogenated
with 50 cc methyl alcohol and 50 cc water, 0.5 g carbon and 3 cc palladium
chloride solution of 2%. After 2 hours the hydrogen absorption comes to a
standstill, after the theoretical quantity of hydrogen has been absorbed. After
concentrating, the isopropylaminomethyl-(3,4-dihydroxyphenyl)carbinolsulfate
crystallizes out. It has a MP of 180°C after refining. | [Brand name]
Medihaler-ISO (3M Pharmaceuticals). | [Therapeutic Function]
Bronchodilator |
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