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ChemicalBook--->CAS DataBase List--->2911610-03-0

2911610-03-0

2911610-03-0 Structure

2911610-03-0 Structure
IdentificationBack Directory
[Name]

Anti-inflammatory agent 51
[CAS]

2911610-03-0
[Synonyms]

Anti-inflammatory agent 51
[Molecular Formula]

C22H22N6O6S
[MOL File]

2911610-03-0.mol
[Molecular Weight]

498.51
Chemical PropertiesBack Directory
[Boiling point ]

749.2±70.0 °C(predicted)
[density ]

1.444±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

9.84±0.50(predicted)
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

Anti-inflammatory agent 51 (compound 11d) is an amide/sulfonamide derivative with anti-inflammatory activities. Anti-inflammatory agent 51 inhibits NF-κB activation, has the potential for acute lung injury and ulcerative colitis research[1].
[in vivo]

Anti-inflammatory agent 51 (compound 11d) improved LPS-induced acute lung injury (ALI) and alleviated DSS-induced ulcerative colitis in mice[1].

[References]

[1] Pan Chen, et al. Design, synthesis, and bioactivity evaluation of novel amide/sulfonamide derivatives as potential anti-inflammatory agents against acute lung injury and ulcerative colitis. Eur J Med Chem. 2023 Aug 2;259:115706. DOI:10.1016/j.ejmech.2023.115706
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