Identification | Back Directory | [Name]
pectolinarin | [CAS]
28978-02-1 | [Synonyms]
Neolinarin pectolinarin PECTOLINARIN(P) Pectolinaroside Pectolinarin >=98% (HPLC) 5-hydroxy-6-methoxy-2-(4-methoxyphenyl)- 4H-1-Benzopyran-4-one,7-[[6-O-(6-deoxy-α-L- 7-[(6-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyl)oxy]-5-hydroxy-4',6-dimethoxyflavone 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)- 5-Hydroxy-6-methoxy-2-(4-methoxyphenyl)-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one | [Molecular Formula]
C29H34O15 | [MDL Number]
MFCD12407436 | [MOL File]
28978-02-1.mol | [Molecular Weight]
622.57 |
Chemical Properties | Back Directory | [Melting point ]
>250°C (dec.) | [Boiling point ]
896.4±65.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly, Heated), Pyridine (Slightly) | [form ]
Solid | [pka]
6.09±0.40(Predicted) | [color ]
Off-White to Pale Yellow |
Hazard Information | Back Directory | [Chemical Properties]
Yellow powder | [Uses]
antiinflammatory, analgesic | [Definition]
ChEBI: Pectolinarin is a disaccharide derivative that consists of pectolinarigenin substituted by a 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an apoptosis inducer, an anti-inflammatory agent, a plant metabolite, an antineoplastic agent, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an antioxidant. It is a dimethoxyflavone, a rutinoside, a glycosyloxyflavone, a disaccharide derivative and a monohydroxyflavanone. It is functionally related to a pectolinarigenin. | [Biological Activity]
Pectolinarinexerts anti-inflammatoryantioxidantantidiabeticand antitumor activities. It is known to be a potent agent for the treatment of neurodegenerative disorders. It also displays antiviraland antiparasitic effects and can inhibit bacterial biofilm formation. Pectolinarin relieves lipopolysaccharide-induced liver and kidney injuries. | [target]
COX | NF-kB | PGE |
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