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ChemicalBook--->CAS DataBase List--->28875-92-5

28875-92-5

28875-92-5 Structure

28875-92-5 Structure
IdentificationBack Directory
[Name]

MK 485
[CAS]

28875-92-5
[Synonyms]

MK 485
R-(+)-Carbidopa
Carbidopa Impurity 12
Carbidopa Impurity 18
Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-a-methyl-, (R)-
Benzenepropanoic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, (αR)-
Hydrocinnamic acid, α-hydrazino-3,4-dihydroxy-α-methyl-, D- (8CI)
Benzenepropanoic acid, α-hydrazinyl-3,4-dihydroxy-α-methyl-, (αR)-
[Molecular Formula]

C10H14N2O4
[MDL Number]

MFCD28138272
[MOL File]

28875-92-5.mol
[Molecular Weight]

226.23
Chemical PropertiesBack Directory
[Melting point ]

>163°C (dec.)
[Boiling point ]

528.7±50.0 °C(Predicted)
[density ]

1.420±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, Refrigerator, under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
[form ]

Solid
[pka]

3.40±0.14(Predicted)
[color ]

Off-White to Beige
[Stability:]

Hygroscopic
[InChI]

InChI=1/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/s3
[InChIKey]

TZFNLOMSOLWIDK-JQHDBZEONA-N
[SMILES]

[C@](C)(NN)(C(=O)O)CC1C=CC(O)=C(O)C=1 |&1:0,r|
Hazard InformationBack Directory
[Uses]

R-(+)-Carbidopa is an inhibitor of DOPA decarboxylase, which plays a significant role in the prevention of the conversion of L-DOPA (D533751) to dopamine (D533780). Studies has also indicated the inhibitory effects of towards L-DOPA in human liver prepns and as well as 5-hydroxytryptophan (H975700).
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