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ChemicalBook--->CAS DataBase List--->287937-12-6

287937-12-6

287937-12-6 Structure

287937-12-6 Structure
IdentificationBack Directory
[Name]

O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE
[CAS]

287937-12-6
[Synonyms]

VIRODHAMINE
AURORA KA-7837
O-(2-AMINOETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENOATE
5,8,11,14-Eicosatetraenoic acid, 2-aminoethyl ester, (5Z,8Z,11Z,14Z)-
[Molecular Formula]

C22H37NO2
[MDL Number]

MFCD06654562
[MOL File]

287937-12-6.mol
[Molecular Weight]

347.53
Chemical PropertiesBack Directory
[Boiling point ]

450.3±45.0 °C(Predicted)
[density ]

0.930±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at -20°C
[form ]

Viscous Liquid
[pka]

7.68±0.10(Predicted)
[color ]

Yellow to brown
Hazard InformationBack Directory
[Uses]

Virodhamine is an endogenous cannabinoid receptor mixed antagonist/agonist.
[Definition]

ChEBI: O-Arachidonoyl ethanolamine is a fatty acid ester.
[Biological Activity]

Endogenous cannabinoid receptor mixed agonist/antagonist found in higher concentrations peripherally than anandamide. Full agonist at GPR55 and CB 2 and partial agonist/antagonist at CB 1 (EC 50 values are 12, 381 and 2920 nM at GPR55, CB 2 and CB 1 receptors respectively). Induces hypothermia in vivo . Also available as part of the Cannabinoid Receptor Agonist Tocriset™ and Endocannabinoid Tocriset™ .
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