Identification | Back Directory | [Name]
HEXADIMETHRINE BROMIDE | [CAS]
28728-55-4 | [Synonyms]
POLYBRENE 6,3-ionene sequa-brene POLYBRENE (R)) SEQUA-BRENE(TM) 6,3-ionenebromide HEXADIMETHRIN BROMIDE HEXADIMETHRINE BROMIDE HEXADIMETHRINE BROMIDE, >=95% Sequa-brene,Hexadimethrine bromide, Polybrene HEXADIMETHRIN BROMIDE, FOR PROTEIN SEQUE NCE ANALYSIS 1,5-DIMETHYL-1,5-DIAZAUNDECAMETHYLENE POLYMETHOBROMIDE poly((dimethyliminio)hexamethylene(dimethylimino)trimethylenedibromide) POLY(N,N,N',N'-TETRAMETHYL-N-TRIMETHYLENEHEXAMETHYLENEDIAMMONIUM DIBROMIDE) Poly(dimethyliminio)-1,3-propanediyl(dimethyliminio)-1,6-hexanediyl dibromide Hexadimethrine bromide,1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene | [Molecular Formula]
C39H90Br6N6X2 | [MDL Number]
MFCD00133397 | [MOL File]
28728-55-4.mol | [Molecular Weight]
1122.6 |
Chemical Properties | Back Directory | [storage temp. ]
2-8°C
| [solubility ]
H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow
| [form ]
gelatinous solid
| [color ]
White to off-white | [Water Solubility ]
10mg/ml in Water | [Merck ]
13,4702 | [CAS DataBase Reference]
28728-55-4 |
Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [RIDADR ]
2811 | [WGK Germany ]
3
| [RTECS ]
TQ2655000
| [F ]
3-10 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
Polymers with mol wt of 5000-10,000 have LD50 i.v. in mice: 25-40 mg/kg (Kimura) |
Hazard Information | Back Directory | [Uses]
Antiheparin agent. A 3mg quantity has been found to enhance peptide degradation in automated sequential analysis. | [Uses]
Hexadimethrine bromide can be used to transfect mammalian cells with DNA. It can be used to increase the efficiency of lipofection transfections. Hexadimethrine bromide has been used for lentivirus infection in cells. It has been used for infection of cells with retroviral supernatant. | [Uses]
Used as a protein/peptide carrier for protein sequencing. | [Definition]
ChEBI: Hexadimethrine bromide is a polymer. | [General Description]
Hexadimethrine bromide is a quaternary ammonium compound which works as a heparin antagonist. It is also involved in the transformation of low molecular weight DNA. | [storage]
Store at 2-8℃, stored under nitrogen | [Purification Methods]
Purify it by chromatography on Dowex 50 and/or by filtration through alumina before use [Frank Hoppe-Seyler's Z Physiol Chemie 360 997 1979]. It is hygroscopic, and its solubility in H2O is 10%. |
|
Company Name: |
Spectrum Chemical Manufacturing Corp.
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Tel: |
021-021-021-67601398-809-809-809 15221380277 |
Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
Company Name: |
Sigma-Aldrich
|
Tel: |
021-61415566 800-8193336 |
Website: |
https://www.sigmaaldrich.cn |
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