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ChemicalBook--->CAS DataBase List--->2756566-45-5

2756566-45-5

2756566-45-5 Structure

2756566-45-5 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2756566-45-5
[Synonyms]

UZH2
[Molecular Formula]

C27H37F2N7O
[MOL File]

2756566-45-5.mol
[Molecular Weight]

513.64
Chemical PropertiesBack Directory
[Boiling point ]

724.9±60.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

14.26±0.20(Predicted)
[color ]

White to off-white
Spectrum DetailBack Directory
[Spectrum Detail]

INDEX NAME NOT YET ASSIGNED(2756566-45-5)1HNMR
Hazard InformationBack Directory
[Biological Activity]

UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
[References]

[1]. Dolbois A, et al. 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. J Med Chem. 2021 Sep 9;64(17):12738-12760.
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