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ChemicalBook--->CAS DataBase List--->267654-00-2

267654-00-2

267654-00-2 Structure

267654-00-2 Structure
IdentificationBack Directory
[Name]

BML-259
[CAS]

267654-00-2
[Synonyms]

BML-259
CAY10554
2-phenyl-N-(5-propan-2-yl-1,3-thiazol-2-yl)acetamide
Benzeneacetamide, N-[5-(1-methylethyl)-2-thiazolyl]-
[Molecular Formula]

C14H16N2OS
[MDL Number]

MFCD09802287
[MOL File]

267654-00-2.mol
[Molecular Weight]

260.35
Chemical PropertiesBack Directory
[Melting point ]

150-152℃
[storage temp. ]

RT
[solubility ]

Soluble in DMSO (up to 25 mg/ml).
[form ]

White solid.
[color ]

white
[Stability:]

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard InformationBack Directory
[Description]

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1
[Definition]

ChEBI: 2-phenyl-N-(5-propan-2-yl-2-thiazolyl)acetamide is a member of acetamides.
[storage]

Store at -20°C
[References]

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521
Spectrum DetailBack Directory
[Spectrum Detail]

BML-259(267654-00-2)1HNMR
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