Identification | Back Directory | [Name]
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, 1-[[[(1S)-1-formyl-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]amino]carbonyl]hexahydro-, phenylmethyl ester, (3aR,6aS)- | [CAS]
2663837-73-6 | [Synonyms]
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, 1-[[[(1S)-1-formyl-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]amino]carbonyl]hexahydro-, phenylmethyl ester, (3aR,6aS)- | [Molecular Formula]
C23H29N3O5 | [MOL File]
2663837-73-6.mol | [Molecular Weight]
427.49 |
Hazard Information | Back Directory | [Description]
UAWJ9-36-1 is a SARS-CoV-2 Protease inhibitor (IC50 = 51 nM). UAWJ9-36-1 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HKU1. UAWJ9-36-1 is a promising candidate to be further developed as a broad-spectrum coronavirus antiviral. |
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