| Identification | Back Directory | [Name]
Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- | [CAS]
2654741-64-5 | [Synonyms]
SOS1-IN-11
SOS1 inhibitor
Pyrido[3,4-d]pyridazin-1-amine, 4-methyl-N-[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]-7-(4-morpholinyl)- | [Molecular Formula]
C22H24F3N5O | [MOL File]
2654741-64-5.mol | [Molecular Weight]
431.45 |
| Chemical Properties | Back Directory | [Boiling point ]
596.8±50.0 °C(Predicted) | [density ]
1.307±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (231.78 mM; Need ultrasonic) | [form ]
Solid | [pka]
7.92±0.30(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
SOS1-IN-11 is a potent SOS1 inhibitor with an IC50 value of 30 nM. | [References]
[1]. Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429 A1. |
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