| Identification | Back Directory | [Name]
4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- | [CAS]
2615911-12-9 | [Synonyms]
DEPTOR-IN-1
4H,8H-Pyrano[2,3-f][1,3]benzoxazin-4-one, 2-(3,4-dichlorophenyl)-9-[(3-fluorophenyl)methyl]-9,10-dihydro-3-hydroxy- | [Molecular Formula]
C24H16Cl2FNO4 | [MOL File]
2615911-12-9.mol | [Molecular Weight]
472.29 |
| Chemical Properties | Back Directory | [Boiling point ]
617.1±55.0 °C(Predicted) | [density ]
1.525±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
7.96±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM. | [storage]
Store at -20°C | [References]
[1]. Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64(20):14942-14954. |
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