Identification | Back Directory | [Name]
FRATIDE | [CAS]
251087-38-4 | [Synonyms]
FRATIDE M.W. 4534.11 C192H327N67O60 L-Glutamine, L-seryl-L-glutaminyl-L-prolyl-L-a-glutamyl-L-threonyl-L-arginyl-L-threonylglycyl-L-a-aspartyl-L-a-aspartyl-L-a-aspartyl-L-prolyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-glut
aminyl-L-leucyl-L-valyl-L-leucyl-L-serylglycyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-lysyl-L-a-glut L-Glutamine, L-seryl-L-glutaminyl-L-prolyl-L-a-glutamyl-L-threonyl-L-arginyl-L-threonylglycyl-L-a-aspartyl-L-a-aspartyl-L-a-aspartyl-L-prolyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-glut
aminyl-L-leucyl-L-valyl-L-leucyl-L-serylglycyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-lysyl-L-a-glutamyl-L-alanyl-L-valyl-L-arginyl-L-arginyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-arginyl-L-leucyl- (9
CI) L-Seryl-L-glutaminyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-arginyl-L-threonylglycyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alpha-aspartyl-L-prolyl-L-histidyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-glutaminyl-L-leucyl-L-valyl-L-leucyl-L-serylglycyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-lysyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-arginyl-L-arginyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-arginyl-L-leucyl-L-glutamine | [Molecular Formula]
C192H327N67O60 | [MDL Number]
MFCD04974166 |
Hazard Information | Back Directory | [Description]
Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from FRAT1, the mammalian version of GSK-3-binding protein. Binds to GSK-3, inhibiting its interaction with axin, and also blocks GSK-3-catalyzed phosphorylation of axin and β-catenin. Does not affect GSK-3-mediated phosphorylation of glycogen synthase or eIF2B. |
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