Identification | Back Directory | [Name]
C16 CERAMIDE | [CAS]
24696-26-2 | [Synonyms]
CERAMIDE-C16 C16 CERAMIDE 16:0 CERAMIDE PALMITOYL CERAMIDE N-PALMITOYL CERAMIDE C16-D-ERYTHRO-CERAMIDE N-Palmitoylsphingosine N-PALMITOYL-D-SPHINGOSINE C16 Ceramide (d18:1/16:0) N-HEXADECANOYL-D-SPHINGOSINE N-PALMITOYLSPHINGOSINE, D-ERYTHRO N-PALMITOYL-D-ERYTHRO-SPHINGOSINE D-ERYTHRO-SPHINGOSINE, N-PALMITOYL N-HEXADECANOYL-D-ERYTHRO-SPHINGOSINE N-Palmitoyl-D-erythro-sphingosineCeramide C16 (2S,3R,4E)-2-N-PalMitoyloctadecasphinga-4-ene C16 Ceramide (N-Palmitoylsphingosine, D-erythro) N-PALMITOYL-D-ERYTHRO-SPHINGOSINE SYNTHETICAL 99+% (2S,3R,4E)-2-(Palmitoylamino)-4-octadecene-1,3-diol N-PalMitoyl-D-erythro-sphingosine, synthetical, (99+% E.E.) N-PALMITOYL-D-ERYTHRO-SPHINGOSINE, SYNTHETICAL, 98% (99+% E.E.) N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-Hexadecanamide N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]-hexadecanaMide N-Palmitoyl-D-sphingosine semisynthetic from bovine brain D-sphingosine N-Palmitoyl-D-erythro-sphingosine, N-Hexadecanoyl-D-erythro-sphingosine, Palmitoyl ceramide C16 ceramide, N-Hexadecanoyl-D-sphingosine, N-Palmitoyl-D-erythro-sphingosine, Palmitoyl ceramide | [Molecular Formula]
C34H67NO3 | [MDL Number]
MFCD00056205 | [MOL File]
24696-26-2.mol | [Molecular Weight]
537.9 |
Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
94-95 °C
| [Boiling point ]
614.41°C (rough estimate) | [density ]
0.9596 (rough estimate) | [refractive index ]
1.6630 (estimate) | [storage temp. ]
−20°C | [solubility ]
Soluble in DMF at 0.15mg/ml | [form ]
Crystalline Powder | [pka]
13.54±0.20(Predicted) | [color ]
White | [CAS DataBase Reference]
24696-26-2 |
Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Solid | [Uses]
A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase | [Definition]
ChEBI: N-hexadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a Mycoplasma genitalium metabolite and a human blood serum metabolite. It is a N-acylsphingosine, a Cer(d34:1) and a N-palmitoyl-sphingoid base. It is functionally related to a hexadecanoic acid. | [Biological Activity]
C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In generalceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53. | [storage]
Store at -20°C,protect from light |
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