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ChemicalBook--->CAS DataBase List--->2431-96-1

2431-96-1

2431-96-1 Structure

2431-96-1 Structure
IdentificationBack Directory
[Name]

N,N-DIETHYL-2-PHENYLACETAMIDE
[CAS]

2431-96-1
[Synonyms]

DEPA
n,n-diethylphenylacetamide
phenyl-n,n-diethylacetamide
n,n-diethyl-benzeneacetamid
n,n-diethylbenzeneacetamide
N,N-DIETHYL-2-PHENYLACETAMIDE
n,n-diethyl-2-phenyl-acetamid
BenzeneacetaMide, N,N-diethyl-
N,N-diethyl-2-phenyl-ethanamide
DEPA(N,N-Diethyl-2-phenylacetamide)
[EINECS(EC#)]

219-400-3
[Molecular Formula]

C12H17NO
[MDL Number]

MFCD00192031
[MOL File]

2431-96-1.mol
[Molecular Weight]

191.27
Chemical PropertiesBack Directory
[Boiling point ]

169-171 °C18 mm Hg(lit.)
[density ]

1.004 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.522(lit.)
[Fp ]

>230 °F
Hazard InformationBack Directory
[Uses]

Insect repellent.
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22
[Safety Statements ]

36
[WGK Germany ]

3
[RTECS ]

AB7410000
[Toxicity]

LD50 in guinea pigs, rats, rabbits, mice (g/kg): 7, 3-4, 3.5, ~2 dermally (Rao, 1991)
Questions And AnswerBack Directory
[Description]

N, N-DIETHYL-2-PHENYLACETAMIDE is a safe and effective, low-cost and broad-spectrum repellent for personal protection against Hematophagous arthropods1. It has repellent activity against hematophagous insects including mosquitoes, black flies, horse flies, muscoid flies, rat fleas, and ticks, as well as land leeches and cockroaches.As an Insect repellents, it exert its effects through interactions with Ors (odorant receptors) and GRs (gustatory receptor neuron (GRN)) in mosquitoes. However, the detailed mechanism of action remains inconclusive.
[Referrence]

  1. Kalyanasundaram, Muthuswami, and N. Mathew. "N,N-Diethyl Phenylacetamide (DEPA): A Safe and Effective Repellent for Personal Protection Against Hematophagous Arthropods." Journal of Medical Entomology 43.3(2013):518-25.
  2. Rao, S. S., and K. M. Rao. "Insect Repellent N, N-diethylphenylacetamide: An Update." Journal of Medical Entomology 8.3(1991):303.
  3. Dickens, Joseph C., and J. D. Bohbot. "Mini review: Mode of action of mosquito repellents." Pesticide Biochemistry & Physiology 106.3(2013):149-155.
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