| Identification | Back Directory | [Name]
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- | [CAS]
2413574-64-6 | [Synonyms]
LpxC-IN-10 (Compound A)
3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]- | [Molecular Formula]
C30H31N5O3 | [MOL File]
2413574-64-6.mol | [Molecular Weight]
509.6 |
| Chemical Properties | Back Directory | [Boiling point ]
717.7±70.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
8?+-.0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection[1].
LpxC-IN-10 (Compound A) shows MIC value < 1 pg/mL to E. coli and K. pneumoniae[1]. | [References]
[1]. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1[P]. 2021. |
|
|