| Hazard Information | Back Directory | [Definition]
BMS-502 is a dual DGKα and ζ inhibitor. BMS-502 demonstrated dose-dependent immune stimulation in the mouse OT-1 model, setting the stage for a drug discovery program. BMS-502 demonstrated substantial inhibitory activity against DGKs α, ζ and ι[1].
| [References]
[1] Louis Chupak* and Susan Wee. “Discovery of Potent, Dual-Inhibitors of Diacylglycerol Kinases Alpha and Zeta Guided by Phenotypic Optimization.” ACS Medicinal Chemistry Letters 14 7 (2023): 929–935.
|
|
| Company Name: |
Henan Alpha Chemical Co., Ltd.
|
| Tel: |
0371-0371-55055611 18137792234 |
| Website: |
www.approvedhomemanagement.com/showsupplierproductslist31206/0.htm |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
|