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ChemicalBook--->CAS DataBase List--->2407829-65-4

2407829-65-4

2407829-65-4 Structure

2407829-65-4 Structure
IdentificationBack Directory
[Name]

1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-
[CAS]

2407829-65-4
[Synonyms]

WUN-29654
1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-
[Molecular Formula]

C17H12N2O5
[MDL Number]

MFCD33029299
[MOL File]

2407829-65-4.mol
[Molecular Weight]

324.29
Chemical PropertiesBack Directory
[Boiling point ]

680.0±50.0 °C(Predicted)
[density ]

1.587±0.06 g/cm3(Predicted)
[solubility ]

DMSO : 10 mg/mL (30.84 mM; ultrasonic and adjust pH to 2 with HCl)
[form ]

Solid
[pka]

8.27±0.20(Predicted)
[color ]

Light green to green
Spectrum DetailBack Directory
[Spectrum Detail]

1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-(2407829-65-4)1HNMR
Hazard InformationBack Directory
[Biological Activity]

CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM[1].
[References]

[1]. Nathanael Gray, et al. New crbn modulators. WO2020006262A1.
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