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ChemicalBook--->CAS DataBase List--->2393866-02-7

2393866-02-7

2393866-02-7 Structure

2393866-02-7 Structure
IdentificationBack Directory
[Name]

Bilaid A1
[CAS]

2393866-02-7
[Synonyms]

Bilaid A1
[Molecular Formula]

C28H39N5O4
[MOL File]

2393866-02-7.mol
[Molecular Weight]

509.65
Chemical PropertiesBack Directory
[form ]

A solid
Hazard InformationBack Directory
[Description]

Bilaid A1 is a tetrapeptide agonist of the μ-opioid receptor (Ki = 750 nM in HEK293 cell membranes expressing the human receptor) and a derivative of bilaid A .1 It inhibits forskolin-induced cAMP accumulation by 47% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM.
[References]

1. Dekan, Z., Sianati, S., Yousuf, A., et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor Proc. Natl. Acad. Sci. USA 116(44),22353-22358(2019).
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