| Identification | Back Directory | [Name]
BENFLUOREX HYDROCHLORIDE | [CAS]
23642-66-2 | [Synonyms]
Balans
mediator
LT00134683
Lipophoral
Einecs 245-801-8
LABOTEST-BB LT00134683
BENFLUOREX HYDROCHLORIDE
2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat
2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-ethanobenzoate(est
2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-ethanobenzoate(est
2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride
2-((1-(3-(trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride
2-[[1-Methyl-2-[3-(trifluoroMethyl)-phenyl]ethyl]aMino]ethanol Benzoate HCl Salt
2-((1-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]ETHYL)AMINO)ETHYL BENZOATE HYDROCHLORIDE
2-[[1-METHYL-2-[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE (ESTER) HCL
2-[[1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol benzoate hydrochloride
2-[[1-METHYL-2[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE ESTER HYDROCHLORIDE | [EINECS(EC#)]
245-801-8 | [Molecular Formula]
C19H21ClF3NO2 | [MDL Number]
MFCD00058493 | [MOL File]
23642-66-2.mol | [Molecular Weight]
387.82 |
| Chemical Properties | Back Directory | [Melting point ]
158-159?C | [storage temp. ]
Refrigerator | [solubility ]
Chlorform (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
neat | [color ]
White |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [WGK Germany ]
2
| [RTECS ]
KL8275000
| [Hazard Note ]
Irritant | [HS Code ]
2916399090 | [Toxicity]
LD50 intraperitoneal in mouse: 108mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Originator]
Mediator,Servier,France,1976 | [Uses]
BENFLUOREX HYDROCHLORIDE can be used as an antihyperlipoproteinemic therapeutic and increase of glucose penetration and use by cells.
| [Uses]
Hypolipedimic;Increase of glucose penetration and use by cells | [Manufacturing Process]
To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β-
hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were
added successively 15 parts of 4.7N hydrochloric ether and a solution of 14
parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition
required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from
230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)-
2-(β-benzoyloxyethyl)amino propane hydrochloride
melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts
ether are added, then 10 parts of a concentrated solution of ammonium
hydroxide. The mixture is stirred a few minutes until the salt is dissolved,
then the ethered solution is poured off and dried. After the ether is
eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β-
benzoyloxyethyl)amino propane are obtained; the base is a colorless oil. | [Therapeutic Function]
Antihyperlipidemic, Cardiovascular |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|