| Identification | Back Directory | [Name]
ERYTHROMYCIN GLUCEPTATE (200 MG) | [CAS]
23067-13-2 | [Synonyms]
ilotycingluceptate
erythromycingluceptate
erythrohycingluceptate
erythromycin,glucoheptonate(1:1)
ERYTHROMYCIN GLUCEPTATE (200 MG)
Erythromycin Gluceptate (1246000)
erythromycin,glucoheptonicacidsalt
erythromycin,monoglucoheptonate(salt)
glucoheptonicacid,compd.witherythromycin(1:1)
Erythromycin Gluceptate (200 mg) (DISCONTINUED)
d-glycero-d-gulo-heptonicacid,compd.witherythromycin(1:1) | [EINECS(EC#)]
245-407-6 | [Molecular Formula]
C37H67NO13.C7H14O8 | [MDL Number]
MFCD01729133 | [MOL File]
23067-13-2.mol | [Molecular Weight]
960.11 |
| Chemical Properties | Back Directory | [Melting point ]
95-140° | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Originator]
Ilotycin Gluceptate,Dista,US,1954 | [Uses]
Antibacterial. | [Uses]
Erythromycin Glucoheptonate is a derivative of Erythromycin (E649950), an antibiotic. | [Manufacturing Process]
A solution of 10 grams of d-glucoheptonic acid lactone in 50 ml of distilled
water is warmed on a steam bath for about 2 hours to hydrolyze the lactone
to the acid. The mixture is cooled and 100 ml of 95% ethanol are added. To
the solution of glucoheptonic acid are added about 37 grams of erythromycin
and the volume of the reaction mixture is brought to 200 ml by the addition
of 95% ethanol. The reaction mixture is stirred for about 2 hours and is
filtered through a porcelain filter candle of porosity 02. To provide a sterile
product, aseptic technique is used throughout the remainder of the procedure.
To the filtered solution are added slowly and with stirring about 1,200 ml of
anhydrous ether, to cause precipitation of erythromycin d-glucoheptonate and
to keep in solution any excess of unreacted erythromycin. The precipitated
erythromycin salt is removed by filtration through a sintered glass funnel, is
washed with anhydrous ether and is dried in vacuo. Erythromycin dglucoheptonate melts over a range of about 95° to 140°C. | [Brand name]
Ilotycin (Dista). | [Therapeutic Function]
Antibacterial |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Pharma Affiliates
|
| Tel: |
172-5066494 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList694812/0.htm |
| Company Name: |
Whyte Chemicals
|
| Tel: |
+44 (20) 8346-5946 |
| Website: |
www.whytechemicals.co.uk |
|