| Identification | Back Directory | [Name]
N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine | [CAS]
2305415-83-0 | [Synonyms]
N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine
Propanamide, N-[6-(2-cyanoethoxy)-9-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-9H-purin-2-yl]-2-methyl- | [Molecular Formula]
C36H37N7O4 | [MDL Number]
MFCD32263223 | [MOL File]
2305415-83-0.mol | [Molecular Weight]
631.72 |
| Chemical Properties | Back Directory | [density ]
1.29±0.1 g/cm3(Predicted) | [pka]
9.45±0.43(Predicted) | [InChIKey]
SWIWEMMZHYDBHD-XZWHSSHBSA-N | [SMILES]
C(NC1=NC(OCCC#N)=C2C(=N1)N([C@@H]1O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C1)C=N2)(=O)C(C)C |
| Hazard Information | Back Directory | [Description]
N2-Isobutyryl-O6-cyanoethyl-7'-OH-N-trityl-morpholino guanine is a nucleoside, ribonucleoside, and anti-cancer drug. It is modified with two acyl groups at the 2′ position of the sugar moiety and contains a phosphoramidite group in the 5′ position. It is an activator of DNA synthesis in vitro. In vivo studies have shown that N2-Isobutyryl O6 cyanoethyl 7' OH N trityl morpholino guanine can be used as an anticancer agent against human breast cancer cells. |
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