| Identification | Back Directory | [Name]
PROTAC FAK degrader 1 | [CAS]
2301916-69-6 | [Synonyms]
PROTAC FAK degrader 1 | [Molecular Formula]
C47H56F3N9O8S2 | [Molecular Weight]
996.13 |
| Chemical Properties | Back Directory | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 200 mg/mL (200.78 mM) | [form ]
Solid | [pka]
14.07±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
PROTAC FAK degrader 1 is a selective and potent focal adhesion kinase (Fak) degrader with an IC50 of 6.5 nM, DC50 of 3 nM[1].
IC50: 6.5 nM (Focal adhesion kinase)DC50: 3 nM (Focal adhesion kinase)[1] | [storage]
Store at -20°C | [References]
[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026. |
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