| Identification | Back Directory | [Name]
1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)- | [CAS]
2250019-90-8 | [Synonyms]
1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)- | [Molecular Formula]
C31H31N5O3 | [MOL File]
2250019-90-8.mol | [Molecular Weight]
521.61 |
| Chemical Properties | Back Directory | [Boiling point ]
768.2±60.0 °C(Predicted) | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
powder | [pka]
2.19±0.40(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Biological Activity]
Ned-K is a specific and potent inhibitor of NAADP (nicotinic acid adenine dinucleotide phosphate) signaling th at suppresses Ca2+ oscillations via two-pore channels (TPC1) and opening of the mitochondrial permeability transition pore (mPTP) in cardiomyocytes during simulated ischaemia and reperfusion. Ned-K protected cardiomyocytes from cell death during ischaemia and reperfusion injury in rats. | [storage]
Store at -20°C |
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