| Identification | Back Directory | [Name]
Octanoic acid, 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl][3-[[2-(methylamino)-3,4-dioxo-1-cyclobuten-1-yl]amino]propyl]amino]-, 1-octylnonyl ester | [CAS]
2244716-55-8 | [Synonyms]
heptadecan-9-yl 8-((3-((2-(methylamino)-3,4-dioxocyclobut-1-en-1-yl)amino)propyl)(8-oxo-8-(undecan-3-yloxy)octyl)amino)octanoate
Octanoic acid, 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl][3-[[2-(methylamino)-3,4-dioxo-1-cyclobuten-1-yl]amino]propyl]amino]-, 1-octylnonyl ester | [Molecular Formula]
C52H97N3O6 | [MOL File]
2244716-55-8.mol | [Molecular Weight]
860.34 |
| Chemical Properties | Back Directory | [Boiling point ]
823.8±75.0 °C(Predicted) | [density ]
0.99±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Ethanol: 25 mg/ml | [form ]
Oil | [pka]
9.49±0.50(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
Lipid 29 is an ionizable amino lipid (pKa = 6.91) that has been used in combination with other lipids in the formation of lipid nanoparticles.1 Administration of human erythropoietin (EPO) mRNA in lipid 29-containing lipid nanoparticles increases serum EPO levels in mice. | [References]
1.Cornebise, M., Narayanan, E., Xia, Y., et al.Discovery of a novel amino lipid that improves lipid nanoparticle performance through specific interactions with mRNAAdv. Funct. Mater.32(8)2106727(2106721-2106712)(2021)
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