| Identification | Back Directory | [Name]
6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE | [CAS]
2240-25-7 | [Synonyms]
5-BROMOCYTOSINE
TIMTEC-BB SBB000280
5-BROMOCYTOSINE 99%
5-Bromocytosine,99%
5-Bromocytosine ,97%
5-BROMOCYTOSINE CRYSTALLINE
4-amino-5-bromo-2(1h)-pyrimidinon
4-Amino-5-bromo-2(1H)-pyrimidinone
6-AMINO-5-BROMOPYRIMIDIN-2(1H)-ONE
4-Amino-5-bromopyrimidin-2(1H)-one
6-amino-5-bromo-1H-pyrimidin-2-one
4-Amino-5-bromo-2-hydroxypyrimidine
2(1H)-Pyrimidinone, 4-amino-5-bromo-
2(1H)-Pyrimidinone, 6-amino-5-bromo-
4-aMino-5-broMo-1,2-dihydropyriMidin-2-one | [EINECS(EC#)]
218-806-8 | [Molecular Formula]
C4H4BrN3O | [MDL Number]
MFCD01883049 | [MOL File]
2240-25-7.mol | [Molecular Weight]
190 |
| Chemical Properties | Back Directory | [Appearance]
LIGHT YELLOW AMORPHOUS POWDER | [Melting point ]
240-243 °C (dec.)(lit.)
| [density ]
1.7513 (rough estimate) | [refractive index ]
1.6520 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Soluble in formic acid (50 mg/ml). | [form ]
Solid | [pka]
7.34±0.10(Predicted) | [color ]
White to yellow | [BRN ]
127286 | [NIST Chemistry Reference]
5-Bromocytosine(2240-25-7) |
| Hazard Information | Back Directory | [Chemical Properties]
LIGHT YELLOW AMORPHOUS POWDER | [Uses]
4-Amino-5-bromo-2-hydroxypyrimidine can be used in the synthesis of cross-link products under anaerobic and aerobic conditions. | [General Description]
5-Bromocytosine derivative (β isomer) is a potent anti-HIV agent. | [storage]
Store at -20°C | [Purification Methods]
5-Bromocytosine is recrystallised from H2O or 50% aqueous EtOH. Alternatively, dissolve ca 3g in conc HCl (10mL) and evaporate to dryness. Dissolve the residual hydrochloride in the minimum volume of warm H2O and make faintly alkaline with aqueous NH3. Collect the crystals and dry them in a vacuum at 100o. [Hilbdert & Jensen J Am Chem Soc 56 134 1934, Beilstein 25 III/IV 3689.] |
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