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ChemicalBook--->CAS DataBase List--->2226521-64-6

2226521-64-6

2226521-64-6 Structure

2226521-64-6 Structure
IdentificationBack Directory
[Name]

FM479
[CAS]

2226521-64-6
[Synonyms]

FM479
2-Propenamide, 2-cyano-3-[5-(1-cyclohexyl-1,6-dihydro-6-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furanyl]-N,N-dimethyl-
[Molecular Formula]

C25H26N6O2
[MDL Number]

MFCD31697722
[MOL File]

2226521-64-6.mol
[Molecular Weight]

442.51
Chemical PropertiesBack Directory
[Boiling point ]

735.7±70.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[solubility ]

DMSO: 2mg/mL, clear
[form ]

powder
[pka]

6.39±0.40(Predicted)
Hazard InformationBack Directory
[Biological Activity]

FM-479 is a negative control for FM-381 (HY-102046) and has no activity against JAK3 or other kinases. FM-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909.
[in vitro]

FM-479 is the inactive control of FM-381, the concentration used in assays is similar.

[target]

JAK3

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