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ChemicalBook--->CAS DataBase List--->2225940-51-0

2225940-51-0

2225940-51-0 Structure

2225940-51-0 Structure
IdentificationBack Directory
[Name]

Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
[CAS]

2225940-51-0
[Synonyms]

IUN 40510
Pomalidomide-C7-COOH
8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanoic acid
8-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}octanoic acid
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
[Molecular Formula]

C21H25N3O6
[MDL Number]

MFCD32857157
[MOL File]

2225940-51-0.mol
[Molecular Weight]

415.44
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Biological Activity]

Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].
[storage]

Store at -20°C
[References]

[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.
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