Identification | Back Directory | [Name]
CDK2 INHIBITOR II | [CAS]
222035-13-4 | [Synonyms]
SC 221409 COMPOUND 3 CDK2 INHIBITOR II | [Molecular Formula]
C14H11BrN4O3S | [MDL Number]
MFCD03456380 | [MOL File]
222035-13-4.mol | [Molecular Weight]
395.23 |
Chemical Properties | Back Directory | [Melting point ]
>272°C (dec.) | [density ]
1.85±0.1 g/cm3(Predicted) | [storage temp. ]
Amber Vial, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
8.81±0.20(Predicted) | [color ]
Light Orange to Orange |
Hazard Information | Back Directory | [Description]
The cyclin-dependent kinase 2 (Cdk2) works with cyclins A or E to regulate S phase and G2-M transition during the cell cycle.1 Cdk2 Inhibitor II is a 3-(benzylidne)indolin-2-one analog that selectively and potently inhibits Cdk2 (IC50 = 60 nM).2 It is cell permeable, reversible, and ATP-competitive.2 | [Uses]
CDK2 inhibitor II, is a potent, cell-permeable, ATP-competitive, and selective inhibitor of Cdk2.
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BOC Sciences
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DC Chemicals
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Energy Chemical
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