| Identification | Back Directory | [Name]
PINOSYLVIN | [CAS]
22139-77-1 | [Synonyms]
Pisylvin
Nsc362430
PINOSYLVIN
pinosylvine
AKOS 211-07
(E)-pinosylvin
3,5-stilbenediol
5-Styrylresorcinol
(e)-5-stilbenediol
(E)-3,5-Stilbenediol
3,5-DIHYDROXY-STILBENE
3,5-TRANS-DIHYDROXYSTILBENE
trans-3,5-Dihydroxystilbene
(E)-5-styrylbenzene-1,3-diol
5-(2-Phenylethenyl)benzene-1,3-diol
5-(2-phenylethenyl)-3-benzenedio(e)-
5-[(E)-2-Phenylethenyl]-1,3-benzenediol
(e)-5-(2-phenylethenyl)-1,3-benzenediol
1,3-Benzenediol,5-[(1E)-2-phenylethenyl]- | [EINECS(EC#)]
683-184-0 | [Molecular Formula]
C14H12O2 | [MDL Number]
MFCD00210544 | [MOL File]
22139-77-1.mol | [Molecular Weight]
212.24 |
| Chemical Properties | Back Directory | [Melting point ]
155.5-156° | [Boiling point ]
312.08°C (rough estimate) | [density ]
1.1035 (rough estimate) | [refractive index ]
1.6000 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMF: 10mg/mL; DMF:PBS (pH 7.2) (1:50): 0.01mg/mL; DMSO: 10mg/mL; Ethanol: 20mg/mL; Ethanol:PBS (pH 7.2) (1:50): 0.01mg/mL | [form ]
A solid | [pka]
9.34±0.10(Predicted) | [color ]
White to off-white | [BRN ]
1870942 | [InChI]
InChI=1S/C14H12O2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10,15-16H/b7-6+ | [InChIKey]
YCVPRTHEGLPYPB-VOTSOKGWSA-N | [SMILES]
C1(O)=CC(/C=C/C2=CC=CC=C2)=CC(O)=C1 | [LogP]
3.680 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white crystalline powder | [Uses]
Pinosylvin, a pre-infectious stilbenoid toxin, is used to study its properties as a fungitoxin and therapeutic agent. Pinosylvin is used as a representative stilbene to study its biological actions and therapeutic value in processes such as cell survival, apoptosis and cell mobility. | [Definition]
ChEBI: Pinosylvin is a stilbenol. | [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | [Enzyme inhibitor]
This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. = 155.5-156°C; low solubility in water), also known as (E)-3,5-stilbenediol and trans-3,5-dihydroxystilbene and named systematically as 5-[(E)-2- phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine and other woody plants. Pinosylvin exxhibits micromolar Ki values for specific isozymes of stilbene synthase and chalcone synthase. Target(s): chalcone synthase; stilbene synthase; tyrosinase, or monophenol monooxygenase. | [storage]
4°C, protect from light |
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