| Identification | Back Directory | [Name]
perhydroacenaphthene | [CAS]
2146-36-3 | [Synonyms]
Einecs 218-412-6
perhydroacephthene
perhydroacenaphthene
Decahydroacenaphthene
Dodecahydroacenaphthylene
Acenaphthylene, dodecahydro-
Tricyclo[7.2.1.05,12]dodecane
Tricyclo(6,3,1,04,12)dodecane
Perhydroacenaphthene 2146-36-3 Decahydroacenaphthene | [EINECS(EC#)]
218-412-6 | [Molecular Formula]
C12H20 | [MDL Number]
MFCD00130267 | [MOL File]
2146-36-3.mol | [Molecular Weight]
164.29 |
| Hazard Information | Back Directory | [Uses]
Perhydroacenaphthene or dodecahydroacenaphthylene is used in the synthesis of Alkyladamantanes by the passage of the latter over the alumina catalyst in a flow-type plant with a metal reactor that has application in the field of nanotechnology. | [Preparation]
Perhydro acenaphthene is the main raw material of preparation 1,3-dimethyladamantane, is the important intermediate of preparation Derivatives of Adamantane.Derivatives of Adamantane is a kind of excellent antidementia agent, clinical research confirmation its have good efficacy to vascular dementia.
The synthesis of Perhydroacenaphthene:
1) adding industrial acenaphthylene to 95% ethanol, heating, refluxing and dissolving, then cooling, crystallizing, centrifuging to obtain refined acenaphthene, and carrying out distillation recycling of the filtrate;
2) adding the refined acenaphthene and a catalyst Raney Ni into a high-pressure kettle, replacing gas in the kettle with hydrogen, filling hydrogen to make the pressure in the kettle rise to 0.8 MPa, heating up to about 180 DEG C, starting a reaction for 5 h, continuously supplementing hydrogen during the reaction, making the pressure in the kettle rise slowly, and allowing the pressure after the reaction to be 4.0 MPa;
3) cooling after the reaction is finished, filtering the catalyst, and thus obtaining the perhydroacenaphthene.
https://patents.google.com/patent/CN105461499A/en |
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