| Identification | Back Directory | [Name]
Ensartinib dihydrochloride | [CAS]
2137030-98-7 | [Synonyms]
X-396 hydrochloride
Ensartinib hydrochloride
Ensartinib dihydrochloride | [Molecular Formula]
C26H28Cl3FN6O3 | [MDL Number]
MFCD31657344 | [MOL File]
2137030-98-7.mol | [Molecular Weight]
597.9 |
| Hazard Information | Back Directory | [Description]
Ensartinib
HCl is the salt form of Ensartinib, an orally available small molecule
inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase
(ALK) with potential antineoplastic activity. Upon oral administration,
X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK
point mutation variants. Inhibition of ALK leads to the disruption of
ALK-mediated signaling and eventually inhibits tumor cell growth in
ALK-expressing tumor cells. ALK belongs to the insulin receptor
superfamily and plays an important role in nervous system development. |
|
| Company Name: |
Wuhan Topule
|
| Tel: |
+86-02787215551 +86-19945035818 |
| Website: |
http://www.topule.com/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|