Identification | Back Directory | [Name]
Mal-amido-PEG2-Val-Cit-PAB-PNP | [CAS]
2112738-13-1 | [Synonyms]
Mal-amido-PEG2-Val-Cit-PAB-PNP | [Molecular Formula]
C39H50N8O14 | [MDL Number]
MFCD30828687 | [MOL File]
2112738-13-1.mol | [Molecular Weight]
854.86 |
Hazard Information | Back Directory | [Description]
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing a maleimide group that can be reacted with thiol containing molecules.. The Val-Cit will specifically be cleaved by Cathepsin B.PNP can be substituted by nucleophiles. | [Biological Activity]
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable ADC linker containing 2 units of PEG, which can be used to synthesize antibody drug conjugates (ADCs). | [in vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | [target]
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Company Name: |
Abydos Scientific
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025-84767922 18936879710 |
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http://www.abydoscientific.com/index.html |
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