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ChemicalBook--->CAS DataBase List--->2095489-35-1

2095489-35-1

2095489-35-1 Structure

2095489-35-1 Structure
IdentificationBack Directory
[Name]

BRF110 >=98% (HPLC)
[CAS]

2095489-35-1
[Synonyms]

BRF110
BRF110 >=98% (HPLC)
[Molecular Formula]

C22H18F3N3O2
[MDL Number]

MFCD31697734
[MOL File]

2095489-35-1.mol
[Molecular Weight]

413.39
Hazard InformationBack Directory
[Description]

BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model.
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