| Identification | Back Directory | [Name]
2-Anthracenesulfonic acid, 1-amino-4-[[4-[(2,4-dimethylphenyl)thio]phenyl]amino]-9,10-dihydro-9,10-dioxo-, sodium salt (1:1) | [CAS]
2089035-40-3 | [Synonyms]
PSB16133
PSB-16133
PSB 16133
PSB-16133 sodium
2-Anthracenesulfonic acid, 1-amino-4-[[4-[(2,4-dimethylphenyl)thio]phenyl]amino]-9,10-dihydro-9,10-dioxo-, sodium salt (1:1) | [Molecular Formula]
C28H23N2NaO5S2 | [MOL File]
2089035-40-3.mol | [Molecular Weight]
554.61 |
| Hazard Information | Back Directory | [Description]
PSB-16133 is a Potent and Selective Antagonist for the UTP-Activated P2Y4 Receptor. PSB-16133 exhibited an IC50 value of 233 nM, selectivity versus other P2Y receptor subtypes, and is thought to act as an allosteric antagonist. A receptor homology model was built and docking studies were performed to analyze ligand-receptor interactions. Compound 64 represents the most potent and selective P2Y4 receptor antagonist known to date and is therefore anticipated to become a useful tool for studying this scarcely investigated receptor. |
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