Identification | Back Directory | [Name]
CYCLO(-TRP-TRP) | [CAS]
20829-55-4 | [Synonyms]
CYCLO(-TRP-TRP) CYCLO(L-TRP-L-TRP) Cyclo(L-Trp-L-Trp)≥ 98% (HPLC) Cyclo(L-tryptophanyl-L-tryptophanyl) (3S,6S)-3,6-Bis(indol-3-ylmethyl)-2,5-piperazinedione (3S,6S)-3,6-bis((1H-Indol-3-yl)methyl)piperazine-2,5-dione 2,5-Piperazinedione, 3,6-bis(1H-indol-3-ylmethyl)-, (3S,6S)- Cyclo(L-Trp-L-Trp) (Cyclic dioxopiperazine-L-tryptophan-L-tryptophan) | [Molecular Formula]
C22H20N4O2 | [MDL Number]
MFCD00237621 | [MOL File]
20829-55-4.mol | [Molecular Weight]
372.42 |
Chemical Properties | Back Directory | [Boiling point ]
813.4±60.0 °C(Predicted) | [density ]
1.364±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
12.86±0.60(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Chemical Properties]
Light yellow powder | [Uses]
Cyclo(L-Trp-L-Trp) is a tryptophan containing diketopiperazines isolated from the culture of the genetically engineered stain Actinosynnema pretiosum which shows moderate cytotoxic activities against HeLa PC3 lines;Also, it is derived from L-Tryptophan (T947210), which is an essential amino acid. |
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