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ChemicalBook--->CAS DataBase List--->2079895-62-6

2079895-62-6

2079895-62-6 Structure

2079895-62-6 Structure
IdentificationBack Directory
[Name]

TP-472
[CAS]

2079895-62-6
[Synonyms]

TP-472
[Molecular Formula]

C20H19N3O2
[MDL Number]

MFCD30536375
[MOL File]

2079895-62-6.mol
[Molecular Weight]

333.38
Chemical PropertiesBack Directory
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: Soluble
[form ]

A solid
[pka]

14.98±0.20(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM; EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic Consortium (SGC) website for more information.
[storage]

Store at -20°C
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