Identification | Back Directory | [Name]
Propargyl-PEG4-S-PEG4-acid | [CAS]
2055041-20-6 | [Synonyms]
Propargyl-PEG4-S-PEG4-acid 4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriacont-30-ynoic acid | [Molecular Formula]
C22H40O10S | [MDL Number]
MFCD29918242 | [MOL File]
2055041-20-6.mol | [Molecular Weight]
496.61 |
Hazard Information | Back Directory | [Description]
Propargyl-PEG4-S-PEG4-acid is a PEG linker containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media. |
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