| Identification | Back Directory | [Name]
JS-K | [CAS]
205432-12-8 | [Synonyms]
JS-K >=97%
1-Piperazinecarboxylic acid, 4-[2-(2,4-dinitrophenoxy)-1-oxidodiazenyl]-, ethyl ester | [Molecular Formula]
C13H16N6O8 | [MDL Number]
MFCD06407868 | [MOL File]
205432-12-8.mol | [Molecular Weight]
384.3 |
| Chemical Properties | Back Directory | [Melting point ]
140-141 °C | [Boiling point ]
546.7±60.0 °C(Predicted) | [density ]
1.60±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 9.3 mg/mL, soluble | [form ]
A crystalline solid | [pka]
-7.23±0.20(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
JS-K belongs to the class of diazeniumdiolate prodrug. It generates nitric oxide when metabolized by glutathione S-transferases (GST), which ensures optimal activity of JS-K. It has tumor growth inhibition action in human prostate cancer and leukemia. |
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