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ChemicalBook--->CAS DataBase List--->205254-94-0

205254-94-0

205254-94-0 Structure

205254-94-0 Structure
IdentificationBack Directory
[Name]

PDGFR Tyrosine Kinase Inhibitor III
[CAS]

205254-94-0
[Synonyms]

PDGFR Tyrosine Kinase Inhibitor III
[Molecular Formula]

C27H27N5O4
[MDL Number]

MFCD09037549
[MOL File]

205254-94-0.mol
[Molecular Weight]

485.53
Chemical PropertiesBack Directory
[Melting point ]

218-219 °C(Solv: chloroform (67-66-3))
[Boiling point ]

713.7±60.0 °C(Predicted)
[density ]

1.310±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

13.18±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

IUN54940, also known as PDGFR Tyrosine Kinase Inhibitor III, is a PDGFR inhibitor.
[Definition]

ChEBI: PDGF receptor tyrosine kinase inhibitor III is an N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a N-arylpiperazine, a N-carbamoylpiperazine, an aromatic ether, a member of phenylureas, a member of quinazolines and a tertiary amino compound.
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