| Identification | Back Directory | [Name]
4-FLUORO-3-NITROBENZYL ALCOHOL 96 | [CAS]
20274-69-5 | [Synonyms]
(4-Fluoro-3-nitrophenyl)methanol
4-Fluoro-3-nitrobenzyl alcohol 96%
Benzenemethanol, 4-fluoro-3-nitro-
4-FLUORO-3-NITROBENZYL ALCOHOL 96 | [Molecular Formula]
C7H6FNO3 | [MDL Number]
MFCD01861396 | [MOL File]
20274-69-5.mol | [Molecular Weight]
171.13 |
| Chemical Properties | Back Directory | [Melting point ]
39-44 °C (lit.) | [Boiling point ]
333.7±27.0 °C(Predicted) | [density ]
1.434 | [Fp ]
230 °F | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
13.37±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
4-Fluoro-3-nitrobenzyl Alcohol is used as a reagent in the preparation of EW-7197 (E950000) which is a highly potent orally bioavailable inhibitor of TGF-β type I receptor kinase that is used in cancer treatment as an immunotherapeutic or antifibrotic agent. | [Uses]
4-Fluoro-3-nitrobenzyl alcohol may be used in the synthesis of 4-fluoro-3-nitrobenzyl chloride. | [General Description]
4-Fluoro-3-nitrobenzyl alcohol can be prepared from the reaction between borane (in THF) and 4-fluoro-3-nitrobenzoic acid (in THF) at 0°C. |
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