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ChemicalBook--->CAS DataBase List--->2010159-60-9

2010159-60-9

2010159-60-9 Structure

2010159-60-9 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand-Linker Conjugates 6 Free Base
[CAS]

2010159-60-9
[Synonyms]

VH032-PEG2-NH2
S)-AHPC-PEG2-NH2
(S,R,S)-AHPC-PEG2-NH2
PROTACs Related Compound 6
VHL Ligand-Linker Conjugates 3
(S,R,S)-AHPC-acetamido-O-C2-amine HCI
(S,R. S)-AHPC-PEG2-amine hydrochloride salt
E3 ligase Ligand-Linker Conjugates 6 Free Base
(S,R,S)-AHPC-PEG2-NH2 (E3 ligase Ligand-Linker Conjugates 6 Free Base)
(2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
(2S,4R)-1-[(2S)-2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
[Molecular Formula]

C28H41N5O6S
[MDL Number]

MFCD31728145
[MOL File]

2010159-60-9.mol
[Molecular Weight]

575.73
Chemical PropertiesBack Directory
[Boiling point ]

856.9±65.0 °C(Predicted)
[density ]

1.249±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Water, DMSO, Methanol
[form ]

Solid
[pka]

13.54±0.46(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2934100090
Hazard InformationBack Directory
[Description]

(S, R, S)-AHPC-PEG2-amine is a synthetic PROTAC linker that incorporates an E3 ligase ligand with a PEG2 unit to empower drug research & discovery. It is reactive with NHS ester or carboxylic acid.
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