Identification | Back Directory | [Name]
N-methyl-2-sulfanylbenzamide | [CAS]
20054-45-9 | [Synonyms]
Axitinib intermediates 2-mercapto-N-methylbenzamid 2-mercapto-N-methylbenzamide N-methyl-2-sulfanylbenzamide 2- Mercapto-N-MethyllbenzaMide 1.2-mercapto-N-methylbenzamide BenzaMide, 2-Mercapto-N-Methyl- Axitinib 2-Mercapto N-Methyl Benzamide TIANFU CHEM N-methyl-2-sulfanylbenzamide N-methyl-2-sulfanylbenzamide ISO 9001:2015 REACH 3-Piperidinecarboxylicacid,4-oxo-,ethylester,hydrochloride(1:2) 2-MERCAPTO-N-METHYL BENZAMIDE(RE-EXPORTWIDE B/E.NO:2513786 DT 08.09.2015) | [EINECS(EC#)]
633-825-5 | [Molecular Formula]
C8H9NOS | [MDL Number]
MFCD00136334 | [MOL File]
20054-45-9.mol | [Molecular Weight]
167.23 |
Chemical Properties | Back Directory | [Melting point ]
94-96 °C | [Boiling point ]
326.2±25.0 °C(Predicted) | [density ]
1.174 | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
5.89±0.43(Predicted) | [color ]
Off-White to Pale Beige | [Stability:]
Air Sensitive | [LogP]
1.360 (est) |
Hazard Information | Back Directory | [Description]
N-methyl-2-sulfanylbenzamide is an axitinib intermediate. | [Uses]
2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib (A794650) which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. | [Application]
2-Mercapto-N-methyl-benzamide is an intermediate used to prepare axitinib which is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. | [Synthesis]
2-mercapto-N-methylbenzamide is prepared by reactig 2,2'-Disulfanediylbis(N-methylbenzamide) and sodium tetrahydroborate In tetrahydrofuran.
|
|
|