| Identification | Back Directory | [Name]
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate | [CAS]
1987887-92-2 | [Synonyms]
Nintedanib-011
Intedanib Impurity D
Nintedanib Impurity q
Nintedanib Impurity 34
Nintedanib impuritiesD
Nintedanib impurities25
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylen...
(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
(Z)-Methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (Nintedanib Impurity)
Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-
(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester | [Molecular Formula]
C24H21N3O3 | [MOL File]
1987887-92-2.mol | [Molecular Weight]
399.44 |
| Chemical Properties | Back Directory | [Melting point ]
273 - 276°C | [Boiling point ]
641.3±55.0 °C(Predicted) | [density ]
1.316±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
11.16±0.20(Predicted) | [color ]
Yellow to Orange |
| Hazard Information | Back Directory | [Uses]
(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy. |
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