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ChemicalBook--->CAS DataBase List--->196965-14-7

196965-14-7

196965-14-7 Structure

196965-14-7 Structure
IdentificationBack Directory
[Name]

SB 221284
[CAS]

196965-14-7
[Synonyms]

SB 221284
5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE
2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
[Molecular Formula]

C16H14F3N3OS
[MOL File]

196965-14-7.mol
[Molecular Weight]

353.36
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

DMSO: ~14 mg/mL, soluble
[form ]

solid
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

SB 221284 is a potent, selective SR-2C/SR-2B antagonist.
[Definition]

ChEBI: SB 221284 is an indolyl carboxylic acid.
[Biological Activity]

Potent, selective 5-HT 2C/2B receptor antagonist. pK i values are 6.4, 7.9 and 8.6 for 5-HT 2A , 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo .
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