| Identification | Back Directory | [Name]
TETRAGASTRIN | [CAS]
1947-37-1 | [Synonyms]
TETRAGASTRIN
CCK-4 Acetate
Trp-Met-Asp-Phe amide
Cholecystokinin(36-39)
Tetragastrin hydrochloride
H-Trp-Met-Asp-Phe-NH2 acetate
Cholecystokinin, CCK Tetrapeptide
CCK-4 Acetate, Gastrin Tetrapeptide
4-7-Cholecystokinin-7 (swine) (9CI)
Cholecystokinin fragment 30-33 amide
Cholecystokinin C-terminal tetrapeptide
Gastrin Tetrapeptide H-Trp-Met-Asp-Phe-NH2
Cholecystokinin Fragment 30-33 Amide >=95% (HPLC)
L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-α-aspartyl-
L-Phenylalaninamide, L-tryptophyl-L-methionyl-L-a-aspartyl-
Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl- (7CI)
Alaninamide, L-tryptophyl-L-methionyl-L-aspartylphenyl-, L- (8CI)
Cholecystokinin Tetrapeptide, Cholecystokinin Octapeptide (5-8), CCK-4, Gastrin (14-17) (huMan)
(3S)-3-[[(1S)-1-carbamoyl-2-phenyl-ethyl]carbamoyl]-3-[[(2S)-2-[[(2S)-3-(1H-indol-3-yl)-2-phenylmethoxycarbonylamino-propanoyl]amino]-4-methylsulfanyl-butanoyl]amino]propanoic acid | [Molecular Formula]
C37H42N6O8S | [MDL Number]
MFCD01741579 | [MOL File]
1947-37-1.mol | [Molecular Weight]
730.83 |
| Chemical Properties | Back Directory | [Melting point ]
185-195 °C | [Boiling point ]
1070.0±65.0 °C(Predicted) | [density ]
1.348±0.06 g/cm3(Predicted) | [storage temp. ]
?20°C | [form ]
Solid | [pka]
4.19±0.10(Predicted) | [color ]
White to off-white |
| Safety Data | Back Directory | [WGK Germany ]
3 | [Toxicity]
dog,LD,intravenous,> 100mg/kg (100mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: EXCITEMENT,Oyo Yakuri. Pharmacometrics. Vol. 3, Pg. 121, 1969. |
| Hazard Information | Back Directory | [Hazard]
Moderately toxic by ingestion | [Uses]
Cholecystokinin Fragment 30-33 Amide can be used for inactivating the CCK8 antiserum. The product can also be used as an antigen utilized in absorption control for testing the specificity of antisera. | [Definition]
ChEBI: Tetragastrin is a tetrapeptide composed of L-tryptophan, L-methione, L-aspartic acid and L-phenylalaninamide residues joined in sequence. It has a role as an anxiogenic and a human metabolite. It is a tetrapeptide and a peptidyl amide. | [Biochem/physiol Actions]
Cholecystokinin Fragment 30-33 Amide also referred to as CCK-4 or Trp-Met-Asp-Phe amide is a peptide fragment derived from peptide hormone cholecystokinin. CCK-4 is a panicogenic agent that induces panic attacks in humans. This property of the compound can be used in scientific research for testing the new anxiolytic drugs. |
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