| Identification | Back Directory | [Name]
2-Pyrimidinamine, 4-(difluoromethyl)-5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)- | [CAS]
1927857-55-3 | [Synonyms]
2-Pyrimidinamine, 4-(difluoromethyl)-5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)- | [Molecular Formula]
C16H20F2N8O2 | [MOL File]
1927857-55-3.mol | [Molecular Weight]
394.38 |
| Hazard Information | Back Directory | [Description]
PQR514 is a potent pan-PI3K inhibitor (Ki 110alpha =2.2 nM). PQR514 is a follow-up compound for the phase-II clinical compound PQR309. PQR514 has an improved potency both in vitro and in cellular assays with respect to its predecessor compounds. It shows superiority in the suppression of cancer cell_x000D_
proliferation and demonstrates significant antitumor activity in an OVCAR-3 xenograft model at concentrations approximately eight times lower than PQR309 |
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| Company Name: |
DC Chemicals
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| Tel: |
021-58447131 13564518121 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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