| Identification | Back Directory | [Name]
3-isomangostin | [CAS]
19275-46-8 | [Synonyms]
3-isomangostin
3-Isomangostin, 98%, from Garcinia mangostana L.
3,4-dihydro-5,9-dihydroxy-8-Methoxy-2,2-diMethyl-7-(3-Methylbut-2-enyl)pyrano[3,2-b]xanthen-6(2H)-one
3,4-Dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2H,6H-pyrano[3,2-b]xanthen-6-one
2H,6H-Pyrano[3,2-b]xanthen-6-one, 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-
5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one | [Molecular Formula]
C24H26O6 | [MDL Number]
MFCD10566618 | [MOL File]
19275-46-8.mol | [Molecular Weight]
410.46 |
| Chemical Properties | Back Directory | [Melting point ]
155～160℃ | [Boiling point ]
615.9±55.0 °C(Predicted) | [density ]
1.257 | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
7.04±0.40(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
3-Isomangostin has been discovered as being a new class of MTH1 inhibitor using X-ray crystallography screening, as well as, an inhibitor of amyloidogenesis, which can reduce amyloid fibril formation by human V30M transthyretin variant. It has also been used to prepare novel xanthone derivative to use against cancer. | [Definition]
ChEBI: 3-Isomangostin is a member of xanthones. |
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